Step-by-Step Laboratory Practicals for IB, IGCSE & GCSE Science

Welcome to Practical Science — a free library of over 100 detailed laboratory practicals, study guides and revision resources for secondary school science students and teachers. Whether you are preparing for your IB Diploma, Edexcel IGCSE or GCSE exams, you will find clear instructions to help you succeed.

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  This Week in Science: Impossible Atmospheres, Diamond Breakthroughs, and Sharks With Friends24/03/2026
  From an ancient planet that defies the laws of physics to bacteria engineered to hunt cancer, this week’s science news spans the cosmos and the deep blue sea. Here are six stories that caught our attention — and might just spark a great classroom discussion.
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IGCSE Prescribed Practicals

Complete step-by-step guides for every Edexcel IGCSE prescribed practical, with methods, safety notes, model data and analysis.

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IB Internal Assessment Help

Preparing your IB Chemistry IA? These guides will help you choose a topic, structure your investigation and score full marks.

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Latest Posts

• IB Biology and Chemistry IA: Analyzing Vitamin C with Titration Methods28/03/2026
  Vitamin C (ascorbic acid, C₆H₈O₆) is an essential nutrient and a reducing agent that is readily oxidised. In this investigation, you will use iodometric titration to measure the vitamin C content of fruit juice after exposure to two continuous variables: temperature and metal ion concentration. Both investigations use the same titration method, making this a versatile and highly scorable IB Chemistry IA topic. This practical is suitable for IB Diploma Chemistry and makes an excellent Internal Assessment (IA) topic.
• IB Biology IA: Beetroot and Cell Membrane Permeability28/03/2026
  IB Biology IA: Beetroot and Cell Membrane Permeability In this investigation, you will use beetroot tissue to explore how increasing temperature affects the permeability of cell membranes. As membranes are damaged by heat, the red pigment anthocyanin leaks out of the vacuole — the more pigment released, the more permeable the membrane has become. A colorimeter is used to measure absorbance quantitatively, making this an excellent IB Biology IA investigation. This practical is suitable for IB Diploma Biology and Edexcel IGCSE Biology students.
• IB Chemistry IA: Enthalpy of Neutralisation Experiment Guide28/03/2026
  In this investigation, you will measure the enthalpy of neutralisation (ΔHₙₑᵤₜ) for a strong acid and a weak acid reacting with a strong base, and use the difference to explore the relationship between enthalpy change and acid dissociation constants (Kₐ and pKₐ). This practical is suitable for IB Diploma Chemistry HL and makes an excellent Internal Assessment (IA) topic.
• IB Chemistry IA: Investigating Reaction Rates with Temperature Changes28/03/2026
  The iodine clock reaction is a classic chemistry experiment that produces a dramatic, sudden colour change from colourless to deep blue-black. In this investigation, you will explore how changing the temperature affects the rate of this reaction and use your results to determine the activation energy of the reaction.

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